Arnoldagger1486

Serous (cystic) neoplasm (SCN) of the pancreas is generally benign, and surgical treatment is recommended only in limited cases. To avoid unnecessary surgery, an accurate diagnosis of SCN is essential. In the present study, we aimed to identify new immunohistochemical markers to distinguish SCN from other tumors.

We compared the comprehensive gene expression profiles of SCN with those of normal pancreas and pancreatic ductal adenocarcinoma (PDAC). We selected the candidate molecules that were upregulated in SCN, minimally expressed or unexpressed in PDAC, and had specific and available antibodies suitable for immunohistochemistry, and further analyzed their immunohistochemical expression in various tumors. We selected AQP1, STRC, FGFR3, and TMEM255B, which were expressed in 79%, 100%, 100%, and 100% of SCN cases, in diffuse SCN cells. AQP1 was not expressed in other tumors except in 20% of mucinous cystic neoplasms (MCNs) and 19% of PDACs. STRC was rarely expressed in MCN, neuroendocrine neoplasm (NEN), and PDAC. FGFR3 was expressed in 31% of intraductal papillary-mucinous neoplasms (IPMNs), 50% of intraductal oncocytic papillary neoplasms (IOPNs), 40% of NENs, 30% of acinar cell carcinomas (ACCs), 40% of solid-pseudopapillary neoplasms (SPNs), and 52% of PDACs. TMEM255B was not expressed in the other tumors except 50% of MCNs, 80% of IPMN gastric subtype, and 29% of PDACs. All antigens were usually expressed in a small part of cells when they were positive in tumors other than in SCN.

These findings indicate that AQP1 and STRC, and potentially TMEM255B may act as SCN markers.

These findings indicate that AQP1 and STRC, and potentially TMEM255B may act as SCN markers.

To date, no study has investigated the association between chewing function and related parameters as a function of the degree of dementia using a finer subdivision of the values of the Mini-Mental State Examination (MMSE).

This study aimed to investigate the differences in chewing function and related parameters as a function of the degree of dementia.

An analysis of cross-sectional data obtained from the OrBiD (Oral Health, Bite Force, and Dementia) pilot study was performed. The participants were stratified into five groups based on the outcomes of the MMSE (no dementia, MMSE 28-30; mild cognitive impairment, MMSE 25-27; mild dementia, MMSE 18-24; moderate dementia, MMSE 10-17; severe dementia, MMSE <10). The chewing efficiency, maximum occlusal force and related parameters (number of supporting zones, number of teeth, Eichner index, tooth/denture status, denture quality, and dental treatment needs) were recorded.

The MMSE groups showed significantly different chewing efficiencies (p=.003, Jonckheere-Terpstra test) and maximum occlusal forces (p=.003, Jonckheere-Terpstra test), but the number of supporting zones (p=.055, chi-square test) and the number of natural teeth (p=.126, chi-square test) were not different. The Eichner index, tooth/denture status, denture quality and dental treatment need showed no significant associations with the degree of dementia.

An improvement in the usability of the measurement methods for assessing chewing function in people with dementia is needed. Research involving people with dementia is necessary because the nutritional situation often deteriorates rapidly within a multifactorial system, which includes chewing ability and oral health.

An improvement in the usability of the measurement methods for assessing chewing function in people with dementia is needed. Research involving people with dementia is necessary because the nutritional situation often deteriorates rapidly within a multifactorial system, which includes chewing ability and oral health.

To explore the experiences of refugees who became registered nurses after arriving to Australia.

Qualitative description using a naturalistic inquiry framework.

Between February 2018 and September 2019, the lead author conducted semi-structured interviews with employed registered nurses (RNs) that are former refugees and English-speaking. Interviews were 45-90min' duration and digitally recorded. Participants provided voluntary informed consent and were sent questions beforehand. Data were collected and coded into themes. Rigor was achieved with multiple transcript readings by the research team to confirm common themes.

Twelve participants discussed their story. Three major themes were identified (1) Milestone of being a refugee; (2) Milestone of resettling in Australia; (3) Milestone of becoming a RN.

Each participant's story started at a place of disadvantage. They progressed successfully through the three milestones; despite living with traumatic experiences, they learned new skills, developed English literacy, became a RN and juggled the demands of life. This paper highlights the poorly understood pockets of the current Australian RN workforce.

The nuanced stories of RNs with refugee backgrounds in this study move beyond trauma and struggle and demonstrate the important journey this particular group of health professionals undertake. Increasing the contextual knowledge of the complex lives of former refugees turned nursing professionals will raise public awareness of the diversity of life experiences of RNs working in Australia.

The nuanced stories of RNs with refugee backgrounds in this study move beyond trauma and struggle and demonstrate the important journey this particular group of health professionals undertake. Increasing the contextual knowledge of the complex lives of former refugees turned nursing professionals will raise public awareness of the diversity of life experiences of RNs working in Australia.

This study aimed to evaluate the oral health status of individuals with obsessive-compulsive disorder (OCD).

Ninety-two participants, aged 18 years and older from which 46 had OCD symptoms, were included in this comparative cross-sectional study. Data on age, sex, smoking habit, educational level, and potential mediators including brushing frequency (BF) and brushing duration (BD) were collected. Clinical examinations determined outcome measures including decayed-missing-filled teeth (DMFT), presence of root caries (PoRC), gingival recession (GR), plaque index (PI), and papillary bleeding index (PBI). Pathway analysis was used for data analysis.

Individuals with OCD had significantly lower DMFT (p < .01), higher BF (p = .01), and lower PI (p = .01); however, there were no significant differences regarding BD, GR, PBI, and PoRC (p > .05). While BD did not have a mediating role, BF mediated the effect of OCD on DMFT (B = -0.31, CI = -0.60 to -0.06) and PI (B = -0.15, CI = -0.36 to -0.03). CDK activation Males had less PI (B = -1.