Kendallholmgaard2291

In contrast to DMEK donor tissue, the artificial lamella is sufficiently robust to allow easy intraocular manipulation without the risk of damaging the implant. It is easily removable and does not require any immunosuppressive treatment because of its nonbiological nature.

Implantation of the EndoArt led to rapid corneal deturgescence and CCT restoration, presenting a possible option for patients with chronic corneal edema.

Implantation of the EndoArt led to rapid corneal deturgescence and CCT restoration, presenting a possible option for patients with chronic corneal edema.

The purpose of this study was to describe the chronic ocular sequelae and subsequent surgical interventions after amniotic membrane transplantation (AMT) in a patient with Stevens-Johnson syndrome (SJS).

A 30-year-old woman was diagnosed with SJS after taking phenytoin prescribed for generalized tonic-clonic seizures. Bedside AMT covering the eyelid margins, the conjunctiva, and the cornea was performed in both eyes during the acute phase during hospitalization. A repeat AMT was necessary after 5 days. After AMT, she was prescribed topical steroids, antibiotics, and artificial tears. She was asked to follow up every 2 weeks in the first 3 months after AMT.

Eyelid-related complications such as trichiasis, distichiasis, eyelid margin keratinization (LMK), and cicatricial entropion developed during the follow-up period within the first year after AMT. Eyelid margin mucous membrane graft (MMG) of all eyelids was performed at the earliest clinical sign of lid-related keratopathy due to LMK. The right eye devons to maintain visual acuity should be explained to patients after acute SJS with ocular involvement.

The purpose of this study was to analyze the evolving trends of surgical techniques and indications of corneal transplantation (CT) at a tertiary hospital in Brazil.

The medical records of all patients who underwent CT at the Hospital Oftalmológico de Sorocaba (Sorocaba Eye Hospital) from the Banco de Olhos de Sorocaba (Sorocaba Eye Bank) group in Sorocaba, Brazil, from January 1, 2012, to December 31, 2019, were analyzed. Data regarding age, sex, transplant indication, and surgical technique were collected.

A total of 16,250 CTs were performed. There was a statistically significant decreasing trend of keratoconus-related CT (P < 0.0001), with rates dropping from 41.7% among all CTs in 2012 to 25.5% in 2019. Penetrating keratoplasty, anterior lamellar keratoplasty, and endothelial keratoplasty (EK) accounted for 59.3%, 27.1%, and 7.8% of the CTs performed in 2012 and 33.3%, 16.4%, and 39.9% in 2019, respectively. A statistically significant decreasing trend was observed for penetrating keratoplasty (P < 0.0001) and anterior lamellar keratoplasty (P < 0.0001), whereas EK showed a statistically significant increasing trend during the period (P < 0.0001). Among EKs, Descemet membrane EK increased statistically significantly from 12.8% in 2012 to 74.4% in 2019 (P < 0.0001).

This study shows relevant evolving trends in indications and preferred CT techniques in a tertiary hospital in Brazil.

This study shows relevant evolving trends in indications and preferred CT techniques in a tertiary hospital in Brazil.

Normally-hearing (NH) listeners rely more on prosodic cues than on lexical-semantic cues for emotion perception in speech. In everyday spoken communication, the ability to decipher conflicting information between prosodic and lexical-semantic cues to emotion can be important for example, in identifying sarcasm or irony. Speech degradation in cochlear implants (CIs) can be sufficiently overcome to identify lexical-semantic cues, but the distortion of voice pitch cues makes it particularly challenging to hear prosody with CIs. The purpose of this study was to examine changes in relative reliance on prosodic and lexical-semantic cues in NH adults listening to spectrally degraded speech and adult CI users. We hypothesized that, compared with NH counterparts, CI users would show increased reliance on lexical-semantic cues and reduced reliance on prosodic cues for emotion perception. We predicted that NH listeners would show a similar pattern when listening to CI-simulated versions of emotional speech.

Sixteen for CI listeners' ability to perceive conflicts between prosodic and lexical-semantic cues, with repercussions for their identification of sarcasm and humor. Understanding instances of sarcasm or humor can impact a person's ability to develop relationships, follow conversation, understand vocal emotion and intended message of a speaker, following jokes, and everyday communication in general.Parkinson's disease is often complicated by psychiatric symptoms. Psychiatrists are caught in a dilemma between such symptoms and physical treatment since Parkinson's disease sometimes shows treatment resistance based on pharmacological treatment-induced dopamine dysfunction. Here, we report on a 64-year-old woman with a 15-year history of Parkinson's disease with stage IV severity based on the Hoehn and Yahr scale. She was admitted to our hospital with a diagnosis of major depressive disorder with psychotic features. Unfortunately, her treatment course for depression was complicated by neuroleptic malignant syndrome. Because we were concerned about the persistence of her depressive symptoms, the risk of psychotropic drugs causing adverse effects, and progressive disuse syndrome, we administered modified electroconvulsive therapy. Her symptoms of neuroleptic malignant syndrome and depression sufficiently improved after five sessions of modified electroconvulsive therapy. Additionally, the primary motor symptoms of her Parkinson's disease also markedly improved. The improvement of neuroleptic malignant syndrome and her motor symptoms based on dopamine dysfunction can be explained by electroconvulsive therapy's effectiveness in activating dopamine neurotransmission. Besides, the marked improvement of her depressive episode with psychotic features was presumed to involve dopamine receptor activation and regulation. NSC 750424 Because advanced Parkinson's disease can sometimes be refractory to treatment based on pharmacological treatment-induced dopamine dysfunction, psychiatrists often have difficulty treating psychiatric symptoms; electroconvulsive therapy may stabilize the dopaminergic system in such cases, presenting a possible non-pharmacologic treatment option for Parkinson's disease.