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t cellular degeneration and significantly reduce oxidative stress.
Extractions of third molars constitute about 90% of the scheduled surgical procedures performed by oral surgeons. Wisdom tooth surgery is associated with complications, such as the lingual and inferior alveolar nerve damage, bleeding, tooth/jaw fractures, tooth displacement into the adjacent anatomical spaces, trismus, infections, and other.
The aim of the study was to analyze complications after wisdom tooth extraction in patients treated at the Department of Oral Surgery of Jagiellonian University Medical College in Kraków, Poland, in the years 2016-2018.
A retrospective analysis of the medical records of 339 patients treated in the outpatient setting was performed. The inclusion criterion comprised a single extraction of a third molar. The exclusion criteria were multiple extractions, comorbidities and pregnancy. No antibiotic prophylaxis was used. The incidence of post-extraction complications, such as oroantral communication, postoperative hematoma, acute inflammation of the surrounding tissues, trdom tooth removal. Complications after the removal of third molars are most often inflammatory.
Lower third molars and the necessity of surgical extraction with root separation are risk factors for postoperative complications in patients who require wisdom tooth removal. Complications after the removal of third molars are most often inflammatory.
In the past 20 years, several studies and clinical trials have reported similar results for transmucosal implants as compared to submerged implants. Several advantages of immediate loading have been pointed out, such as the reduction of treatment time, trauma reduction, and immediate esthetic and functional improvements.
The main objective of this study was to clinically evaluate the implant survival rate in patients with total rehabilitation via implants that underwent immediate loading in the past 5 years.
A cross-sectional, descriptive, observational analysis was conducted. The implant survival rate for an edentulous maxilla or mandible was assessed with regard to the loading protocol by means of a questionnaire and clinical observation. The study included 103 patients with edentulous jaws rehabilitated with fixed prostheses on implants. Each patient received 4-6 implants. In total, 474 implants were placed. Factors such as the implant survival rate as well as biological and prosthetic complications were evaluated and analyzed statistically.
Of the 474 implants initially placed, 458 were considered osteointegrated and 16 were considered lost, which corresponds to a 96.62% implant survival rate. The most common types of failure were prosthetic fractures (46.2%), peri-implantitis (23.1%) and unscrewing (11.5%) in the first 5 years.
The rate of osseointegration for implants placed under immediate loading was extremely high, in accordance with the previously published studies, which led us to conclude that currently, this is a surgical procedure with a high rate of success and high predictability.
The rate of osseointegration for implants placed under immediate loading was extremely high, in accordance with the previously published studies, which led us to conclude that currently, this is a surgical procedure with a high rate of success and high predictability.Long-chain fatty acid oxidation disorders (LC-FAODs) are a group of life-threatening autosomal recessive disorders caused by defects in nuclear genes encoding mitochondrial enzymes involved in the conversion of dietary long-chain fatty acids into energy. Triheptanoin is an odd-carbon, medium-chain triglyceride consisting of 3 fatty acids with 7 carbons each on a glycerol backbone developed to treat adult and pediatric patients with LC-FAODs. The pharmacokinetics of triheptanoin and circulating metabolites were explored in healthy subjects and patients with LC-FAODs using noncompartmental analyses. Systemic exposure to triheptanoin following an oral administration was negligible, as triheptanoin is extensively hydrolyzed to glycerol and heptanoate in the gastrointestinal tract. Multiple peaks for triheptanoin metabolites were observed in the plasma following oral administration of triheptanoin, generally coinciding with the time that meals were served. Heptanoate, the pharmacologically active metabolite of triheptanoin supplementing energy sources in patients with LC-FAODs, showed the greatest exposure among the metabolites of triheptanoin in human plasma following oral administration of triheptanoin. The exposure of heptanoate was approximately 10-fold greater than that of beta-hydroxypentoate, a downstream metabolite of heptanoate. Exposure to triheptanoin metabolites appeared to increase following multiple doses as compared with the single dose, and with the increase in triheptanoin dose levels.
To investigate the relationship between anxiety symptoms and factors related to clinical control and quality of life of children with asthma aged 7-12 years.
A cross-sectional comparative study involving children recruited from a reference center for asthma treatment in the city of Natal-RN. Diagnosis, control and severity were performed following GINA recommendations (2019). Sociodemographic information and spirometry results from a bronchodilator test were collected. learn more Modified Fisher's scale, clinical control questionnaires (c-ACT and ACT), quality of life assessment (PAQLQ) (total score and domains) and anxiety symptoms assessment (SCAS) (total score and domains) were applied.
The sample consisted of 42 children with asthma. Symptoms of social phobia (as identified by SCAS), and household head education were related to clinical asthma control (p = .006; R
= .19). Total SCAS score, guardian's education and physical activity were related to total PAQLQ (p < .0001; R
= .33). SCAS was related to the activity limitation domain of PAQLQ (p = .004; R
= .17). SCAS, gender, and physical activity were related to the PAQLQ symptoms domain (p = .003; R
= .32). The guardian's education, physical activity practice, and the symptoms of separation anxiety, panic attack and agoraphobia (as identified by SCAS) were related to the emotional domain of PAQLQ (p = .004; R
= .45).
The present study shows evidence of an association between anxiety symptoms, poorer clinical control, and health-related quality of life in children with asthma.
The present study shows evidence of an association between anxiety symptoms, poorer clinical control, and health-related quality of life in children with asthma.