Tobiasenastrup0963

ytes.The impact behavior of carbon fiber epoxy bumper brackets reinforced with 2D biaxial and 2D triaxial braids was experimentally and numerically analyzed. For this purpose, a phenomenological damage model was modified and implemented as a user material in ABAQUS. It was hypothesized that all input parameters could be determined from a suitable high-speed test program. Therefore, novel impact test device was designed, developed and integrated into a drop tower. Drop tower tests with different impactor masses and impact velocities at different bumper bracket configurations were conducted to compare the numerically predicted deformation and damage behavior with experimental evidence. Good correlations between simulations and tests were found, both for the global structural deformation, including fracture, and local damage entities in the impact zone. It was proven that the developed phenomenological damage models can be fully applied for present-day industrial problems.In this work the effects of cooking cycle times of marinating juice and reheating on the formation of cholesterol oxidation products (COPs) and heterocyclic amines (HAs) in marinated pig hock were investigated. After the 12th cycle, the total content of COPs was 3.3, 2.0, and 2.0 times higher than that after the 1st cycle in the skin, subcutaneous fat, and lean meat, respectively. The total content of HAs was 5.8, 6.0, and 5.6 times higher than that after the 1st cycle in the skin, subcutaneous fat, and lean meat, respectively. Notably, more COPs were present in the lean meat than in the skin and subcutaneous fat, whereas the content of HAs in the skin was the highest. Compared with the unreheated samples, the total content of COPs and HAs in all tissues increased after reheating at 95 °C for 30 min or at 121 °C for 25 min, but no significant difference was found between different reheating conditions.Asthma is an important respiratory illness. Though pharmacological and biological treatment is well established and is staged according to endotypes and their responses to treatment, novel avenues are being explored. Our focus is complement. In this viewpoint, we evaluate the approach to target complement in this complex hypersensitivity reaction that develops chronicity and has a personal-as well as a societal-cost.Acrylamide, which forms in heat-treated foods with high carbohydrate content, is a probable human carcinogen. This study aimed to evaluate the association between dietary acrylamide intake and lung cancer using data from the Japan Public Health Center based Prospective Study. Our study included 85,303 participants who completed a food frequency questionnaire. Cox proportional hazards regression models were used to assess hazard ratios and 95% confidence intervals (CIs) after adjusting for confounders. After 14.3 years and 15.4 years of mean follow-up period, 1187 and 485 lung cancer cases were identified in men and women, respectively. The multivariable-adjusted hazard ratios of 10-µg/day increment in acrylamide intake were 1.01 (95% CI, 0.99-1.02) in men and 0.98 (95% CI, 0.95-1.02) in women. Compared with the lowest quartile of acrylamide intake, the hazard ratios for the highest quartile were 1.13 (95% CI, 0.95-1.33; p for trend = 0.12) in men and 1.03 (95% CI, 0.78-1.36; p for trend = 0.86) in women in the multivariable-adjusted model. ATM/ATR targets Moreover, there was also no significant association observed in the stratified analysis for histological subtypes of lung cancer. This study demonstrated that dietary acrylamide intake was not associated with increased lung cancer risk in the Japanese population.Wild food plants are important resources for people living in dry areas of Kenya. A botanical inventory of vascular plants of Kitui county was compiled from specimens collected during field investigations in Kitui county, at the East African (EA) herbarium and from literature reporting on plants of Kitui county. To obtain an inventory of wild edible plants found in Kitui county, literature reporting on wild edible plants of Kenya were searched and combined with the use reports obtained from field surveys in Kitui county. A total of 199 wild plants found in Kitui county have the potential of being utilized as foods in different ways. Plant species growing either as trees or shrubs (83 species) and herbs (36 species) are the dominant life forms while the best represented plant families are Leguminosae (25 species) and Malvaceae (17 species). Fruits (124 reports) and leaves (56 reports) are the common plant parts collected for food. Fruits (120 species) and vegetables (44 species) are the common wild food types in Kitui county. Further studies on species distribution are necessary to address conservation concerns that may threaten such plants.Autism spectrum disorders (ASDs) constitute a set of heterogeneous neurodevelopmental conditions, characterized by a wide genetic variability that has led to hypothesize a polygenic origin. The metabolic profiles of patients with ASD suggest a possible implication of mitochondrial pathways. Although different physiological and biochemical studies reported deficits in mitochondrial oxidative phosphorylation in subjects with ASD, the role of mitochondrial DNA variations has remained relatively unexplored. In this review, we report and discuss very recent evidence to demonstrate the key role of mitochondrial disorders in the development of ASD.Sleep and Klotho have both been closely related to the ageing process, both playing a substantial role in the endocrine and immune systems and, thereby, in oxidative stress and chronic inflammation. However, there are no studies elucidating the relationship between sleep and Klotho. Therefore, this study investigated the association of sleep quantity and quality with the shed form of the α-Klotho gene (S-Klotho plasma levels) in sedentary middle-aged adults. A total of 74 volunteers (52.7% women; aged 53.7 ± 5.1) were recruited for the present study. Objective sleep quality parameters (total sleep time (TST), wake after sleep onset (WASO), and sleep efficiency (SE)) were determined using a wrist-worn accelerometer over seven consecutive days, and the subjective sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI; higher scores indicate worse sleep quality). The S-Klotho plasma levels were measured in the ethylenediaminetetraacetic acid plasma using a solid-phase sandwich enzyme-linked immunosorbent assay.