Mcintoshbraun9435

C5 of maxacalcitol was slightly lower (85%) in Taiwanese compared with that in Japanese and AUCinf of maxacalcitol in Taiwanese subjects was contrarily 15.0 (41.6%) higher than that in Japanese subjects, resulted in not much difference in pharmacokinetics of maxacalcitol between Taiwanese and Japanese. Moreover, maxacalcitol was well tolerated in both healthy Taiwanese and Japanese subjects. © 2020 Chugai Pharmaceutical Co. Ltd. this website Published by Elsevier Ltd.Introduction Low sanitary conditions characterize the rural and urban households in Sub-Saharan African region. Those environmental conditions propitiate the transmission of bacterial infections between animals and humans. Campylobacter spp. is a zoonotic bacterium and cause of human gastroenteritis worldwide, whose main symptom is diarrhea. It is normally found in the digestive tract of many farm animals as a commensal but some species cause diseases in animals. It is important to understand the occurrence of these bacteria in animals, as they may also play a role in transmission to humans. The main objective of this review was to describe the prevalence of Campylobacter in animals in Sub-Saharan Africa. We also report findings on antibiotic resistance. Methods We followed PRISMA guidelines to find studies about occurrence of Campylobacter spp. in animals in all countries from Sub-Saharan Africa. PubMed, Cochrane Library, CINAHL, African Index Medicus, African Journals Online, Google Scholar and Science Diretaken to prevent infection by this pathogen in the region and to control antibiotic resistance. © 2020 The Author(s).Background For Transcarpathian region, with a pronounced landscape diversity of territories and significant areas of nature reserves, well water is an important source of drinking water. Screening of the microelement composition of drinking well water in Transcarpathia has not been carried out before. The microelement composition of such well water can be considered as the natural (baseline) indicator of quality. Methods We screened of the microelement (Cu, Zn, Fe, P, Ca, Mg, Mn, Mo, Co, As, Se, I, Br and F) composition of drinking well water in Transcarpathian region (for all 13 districts). Standard methods were used to determination the concentration of chemical elements in well water electrothermal atomic absorption spectroscopy (Cu, Zn, Fe, Mn, Mo, Co), flame photometry (Ca, Mg), inverse voltammetry (total iodine), potentiometry (F, Br), fluorimetric (Se) and spectrophotometric methods (P, As). Results The content of chemical elements in well water varies over a wide range, in particular for Cu 3.27-11.6 nking well water in Transcarpathia are the relatively high content of Fe (typical for different landscape zones), as well as the low content of Se, I and F. The correlation of inter-elements content of chemical elements in drinking well waters of Transcarpathia has been revealed. The most pronounced correlations are observed for such pairs of microelements Co-Mo (r > 0.95), I-Br (r > 0.92), Zn-Br (r > 0.89), Cu-Co (r > 0.84), Se-Co (r > 0.84), Mo-P (r > 0.84), Mo-I (r > 0.82) and Zn-Mo (r > 0.80). © 2020 The Author(s).This paper presents a fuzzy-multiple objective optimization methodology to plan stand-alone electricity generation systems. The optimization process considers three main objectives, namely technology cost, environmental and societal impacts. For each feasible solution of the Pareto set, a system reliability index is evaluated along the lifetime of the project. As a key contribution, the decision making process is carried out by applying a fuzzy satisfaction method (FSM). The FSM accounts simultaneously four key performance indexes (KPI) technical, economic, environmental and social. The novelty of the proposal lies on the inclusion of societal impact (local wealth creation) in the FSM used here to select the more appropriate solution. Previous contributions on FSM only accounts two of four indexes considered in this paper. The methodology was applied in a Colombian case study. The results show the importance of the simultaneous consideration of technical, economic, environmental and social objectives in the evaluation of off-grid energization solutions. © 2020 Published by Elsevier Ltd.Glyphosate (N- (phosphonomethyl) glycine) is one of the most widely used herbicides in the world. In the literature, there are several studies describing the interaction between glyphosate and clay minerals. However, there is a lack of data of this interaction in marine environments. In this research, we examined the adsorption of glyphosate onto montmorillonite in the presence of artificial seawater. Mössbauer data showed that the interaction of the phosphonate group of glyphosate with Fe2+ of montmorillonite prevents its oxidation to Fe3+. X-ray diffractograms showed that glyphosate adsorption takes place only onto the montmorillonite surface and not in its interlayers. Infrared spectroscopy data demonstrate that the interaction between glyphosate and montmorillonite could be through the amino group. FT-IR spectra of aqueous solutions of salts of seawater showed that Ca2+ interacts with glyphosate of the phosphonate group, thus causing an increase in its adsorption onto montmorillonite. However, glyphosate dissolved in 0.50 mol L-1 NaCl and 0.034 mol L-1MgCl2 solutions showed the lowest adsorption onto montmorillonite. In addition, the adsorption of glyphosate onto montmorillonite decreased when the NaCl concentration increased. The results fitted the Sips isotherm model, probably because the Ca2+ interacts with glyphosate, making the adsorption process more homogeneous. Thus, n values for Freundlich and Sips isotherm models decreased with an increase in ionic strength. Glyphosate and ions of artificial seawater increased the pHpzc of montmorillonite. © 2020 The Authors.The effect of the introduction of sexually active rams in spring on LH secretion in ewes after progestagen treatment has been studied. Two rams were induced into a sexually active state by exposure to 2 months of long days (16 h of light/d) from 1 January (SAR), and another 2 rams were exposed to the natural photoperiod, so that they were not sexually activated in spring (control; C). At the end of the long-day period, rams were returned to natural photoperiod conditions. Fifteen ewes synchronized in estrus by intravaginal sponges were assigned to three groups at sponge withdrawal (hour 0) SAR (n = 5), exposed to SAR rams; C (n = 5), exposed to C rams, and ISO (n = 5), kept isolated from rams. Twenty-four hours after pessary removal (hour 0), rams were introduced into the SAR and C groups. Three SAR ewes presented preovulatory LH surges; the proportion was significantly (P less then 0.05) higher in this group (3/5) than in the others (C 0/5, ISO 0/5). SAR introduction induced a more marked (P less then 0.