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959 and 0.929), for total CSA (r = 0.732 and 0.608), and CMJ power (r = 0.933 and 0.896). These results suggest that lean body mass, quadriceps' CSA and CMJ should be monitored regularly in female weightlifters to detect potential modifications in lifting performance.Cement-stabilized rammed earth (CSRE) is a sustainable construction material. The use of it allows for economizing on the cost of a structure. These two properties of CSRE are based on the fact that the soil used for the rammed mixture is usually dug close to the construction site, so it has random characteristics. That is the reason for the lack of widely accepted prescriptions for CSRE mixture, which could ascertain high enough compressive strength. Therefore, assessing which components of CSRE have the highest impact on its compressive strength becomes an important issue. There are three machine learning regression tools, i.e., artificial neural networks, decision tree, and random forest, used for predicting the compressive strength based on the relative content of CSRE composites (clay, silt, sand, gravel, cement, and water content). The database consisted of 434 samples of CSRE, which were prepared and crushed for testing purposes. Relatively low prediction errors of aforementioned models allowed for the use of explainable artificial intelligence tools (drop-out loss, mean squared error reduction, accumulated local effect) to rank the influence of the ingredients on the dependent variable-the compressive strength. Consistent results from all above-mentioned methods are discussed and compared to some statistical analysis of selected features. This innovative approach, helpful in designing the construction material is a solid base for reliable conclusions.Achieving the shift towards Industry 4.0 is only feasible through the active integration of the shopfloor into the transformation process. Several shopfloor management (SM) systems can aid this conversion. They form two major factions. The first includes methodologies such as Balanced Scorecard (BSC). A defining feature is rigid structures to fixate on pre-defined goals. Other SM strategies instead concentrate on continuous improvement by giving directions. An example of this group is the "HOSHIN KANRI TREE" (HKT). One way of analyzing the dissimilarities, the advantages and disadvantages of these groups, is to examine the neurological patterns of workers as they are applying these. This paper aims to achieve this evaluation through non-invasive electroencephalography (EEG) sensors, which capture the electrical activity of the brain. A deep learning (DL) soft sensor is used to classify the recorded data with an accuracy of 96.5%. Through this result and an analysis using the correlations of the EEG signals, it has been possible to detect relevant characteristics and differences in the brain's activity. In conclusion, these findings are expected to help assess SM systems and give guidance to Industry 4.0 leaders.We investigated the immunogenicity of allogeneic human adipose-derived mesenchymal stem cells (ADSCs) through the production of alloreactive-CD8 T and -memory CD8 T cells, based on their human leukocyte antigen (HLA) expression. In surface antigen analysis, ADSCs do not express co-stimulatory molecules, but expresses HLA-ABC, which is further increased by exposure to the pro-inflammatory cytokines as well as IFN-γ alone. For immunogenicity analysis, allogeneic ADSCs cultured in xenofree medium (XF-ADSCs) were incubated with the recipient immune cells for allogeneic-antigen stimulation. As a result, XF-ADSCs induced IFN-γ and IL-17A release by alloreactive-CD8 T cells and the production of alloreactive-CD8 T cell through a direct pathway, although they have immunomodulatory activity. In the analysis of alloreactive memory CD8 T cells, XF-ADSCs also significantly induced the production of CFSE-low-CD8 TEM and -CD8 TCM cells. However, HLA-blocking antibodies significantly inhibited the production of CFSE-low memory-CD8 T cells, indicating that HLAs are the main antigens responsible for the development of allogeneic ADSCs' immunogenicity. These results suggested that HLA surface antigens expressed in allogeneic MSCs should be solved in order to address concerns related to the immunogenicity problem.Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and mortality and posing a great threat to human health. Because of the diversity of influenza virus strains and drug resistance to the current direct antiviral agents, there have been no effective drugs as yet to cure all patients infected by influenza viruses. Natural products from plants contain compounds with diverse structures that have the potential to interact with multiple host and virus factors. In this study, we identified the ethanol extract of Caesalpinia decapetala (Roth) Alston (EEC) as an inhibitor against the replication of a panel of influenza A and B viruses both on human pulmonary epithelial A549 and human monocytic U937 cells. The animal study revealed that EEC administration reduces the weight loss and improves the survival rate of mice infected with lethal influenza virus. Also, EEC treatment attenuated lung injury and reduced virus titer significantly. In conclusion, we showed that EEC has antiviral activity both in vitro and in vivo, suggesting that the plant C. HKI-272 decapetala has the potential to be further developed as a resource of new anti-influenza drugs.Background nowadays, primary aldosteronism (PA) is suggested to be the most frequent cause of secondary hypertension and it reaches 10% of whole hypertensive population. The CYP11B2 promoter polymorphism might cause aldosterone overproduction. The aim of this study was to establish whether the polymorphism CYP11B2 promoter has a significant impact on diagnostic of PA. Material and methods study group consisted of 239 hypertensive patients previously diagnosed with adrenal incidentaloma. For diagnose of PA were performed screening test-aldosterone-renin ratio (ARR) and saline suppression test (SIT) as a confirmatory test. Genotyping was carried out by the real time PCR method. The significance of differences between the groups was evaluated through Student's t-test. Results our study revealed that genotype TT had plasma aldosterone concentration (PAC), ARR and SIT significantly higher in comparison with CC patients. The mean PAC in CC was 12.71 ng/dL vs. 20.55 ng/dL in TT patients (p = 0.037), which consequently gave a higher ARR in TT patients (119 vs.