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der age and uncontrolled blood pressure were predictors of LVH. Therefore, tailored interventions targeting BP control to reduce the magnitude of LVH and other early complications of hypertension deemed to be compulsory.

In this study, a significant proportion of patients with uncontrolled BP and LVH were found. Abdominal obesity, older age and uncontrolled blood pressure were predictors of LVH. Therefore, tailored interventions targeting BP control to reduce the magnitude of LVH and other early complications of hypertension deemed to be compulsory.

Doctors are often ill-prepared to become patients, despite knowing the technicalities of surgical procedures and the day-to-day workings of hospital life intimately. Surrendering the decision-making process to other healthcare professionals can be an unnerving process for many of those who are medically qualified.

Although the sequelae of prostatectomy have often been written about, little is in the literature from medically qualified patients about their personal experiences of the procedure. We aimed to highlight areas where communication between medically qualified patients and their carers may be strengthened.

We present a personal perspective of the emotional issues surrounding a potential cancer diagnosis, the experience of having a prostatectomy and what the hospital encounters were like in reality with a viewpoint of informing the medical profession in providing better patient information when they ask "what will it be like?". From this perspective, the critical role of the cancer specialist nur else. However, the central role of the cancer specialist nurse as the bridge between the medical team and the patient should not be underestimated.Artificial intelligence (AI) pertains to the ability of computers or computer-controlled machines to perform activities that demand the cognitive function and performance level of the human brain. The use of AI in medicine and health care is growing rapidly, significantly impacting areas such as medical diagnostics, drug development, treatment personalization, supportive health services, genomics, and public health management. AI offers several advantages; however, its rampant rise in health care also raises concerns regarding legal liability, ethics, and data privacy. learn more Technological singularity (TS) is a hypothetical future point in time when AI will surpass human intelligence. If it occurs, TS in health care would imply the replacement of human medical practitioners with AI-guided robots and peripheral systems. Considering the pace at which technological advances are taking place in the arena of AI, and the pace at which AI is being integrated with health care systems, it is not be unreasonable to believe that TS in health care might occur in the near future and that AI-enabled services will profoundly augment the capabilities of doctors, if not completely replace them. There is a need to understand the associated challenges so that we may better prepare the health care system and society to embrace such a change - if it happens.

To determine the prevalence and the risk factors of diabetic peripheral neuropathy (DPN) in hospitalized adult Saudi diabetics.

This is a retrospective, nested case-control study conducted at King Abdulaziz Medical City (KAMC) in Riyadh, Saudi Arabia. All diabetic patients admitted to the hospital between the January 1, and December 31, 2018 were considered for inclusion in the study. Patients with DPN were identified and three controls per case were randomly selected from the remaining diabetic patients without peripheral neuropathy (PN).

A total of 2,096 adult diabetic patients were identified during the study period. Of these, 73 patients (3.5%) were confirmed to be suffering from DPN and 219 were included as controls. When comparing diabetic with the control cases, DPN cases were significantly older (

=0.002), had a significantly higher proportion of type 2 diabetes (

=0.023), chronic kidney disease (

<0.0001), cerebral vascular stroke (

=0.027), hypertension (

=0.005), dyslipidemia (

=0.00gns aimed at risk reduction of cardiovascular and chronic diseases, and consequently progression of DPN.

Acute myeloid leukemia (AML) is a common hematological malignancy associated with different cytogenetic and genetic abnormalities.

FLT3-internal tandem duplication (FLT3/ITD) mutation and CD34 expression levels were assessed in the bone marrow (BM) aspirates of 153 de novo AML patients. Data were correlated with relevant clinic-pathological features of the patients, response to treatment, disease-free survival (DFS), and overall free survival (OS) rates.

FLT3-ITD mutation was detected in 27/153 (17.6%) AML patients (

=0.001), and CD34 was expressed in 83/153 (54.2%) patients (

=0.293) compared to those with wild FLT3 and CD34

expression, respectively. Patients with FLT3-ITD mutation showed increased peripheral blood and BM blast cells, abnormal cytogenetics, poor DFS and OS compared to those with wild FLT3 (

=0.013,

<0.001,

=0.010,

=0.008 and

=0.004, respectively), while there was no significant association with response to treatment (

=0.081). There was no significant association between CD34 expression and response to treatment, DFS, and OS (

>0.05). FLT3-ITD mutation and FAB subtypes were independent prognostic factors for DFS. Older age ≥39 years, HB <7 mg/dL PB blast ≥54%, and FLT3-ITD mutation were independent prognostic factors for poor OS in AML patients. The presence of both FLT3-ITD mutation and CD34 expression associated significantly with resistance to therapy (

=0.024), short DFS and OS rates (

=0.006,

=0.037, respectively).

Combined expression of both FLT3-ITD mutation and CD34 expression is an important prognostic and predictive factor for poor disease outcome in AML patients.

Combined expression of both FLT3-ITD mutation and CD34 expression is an important prognostic and predictive factor for poor disease outcome in AML patients.Group B streptococcus (GBS) is a rare cause of meningitis in adults that commonly affects patients with multiple underlying comorbidities. Although it is uncommon, it typically progresses very rapidly and has a high mortality rate as compared to other causes of bacterial meningitis. Here, we report a patient with GBS meningitis who had no underlying medical illness and presented with multiple episodes of seizure within hours of developing fever. Cerebrospinal fluid analysis results were consistent with bacterial meningitis, and blood cultures grew GBS. She was treated with intravenous ceftriaxone for 2 weeks and made a great recovery without any sequalae. In conclusion, although GBS meningitis is uncommon in adults, it is a serious medical disease and associated with a high mortality rate. To the best of our knowledge, this patient represents one of the few reported cases of GBS meningitis in a previously healthy young adult.